Preclinical Neuroscience platform
The Preclinical Neuroscience Platform (PNP) provides efficient facilities, equipment and support, suitable and dedicated to translational neuroscience and neurodevice research in rodent and rabbit models.
To reach this goal, the platform includes two areas with two support teams:
An animal facility combining housing of animals under defined hygiene standards and experimental areas to conduct animal research experiments.
Lab areas providing four facilities to carry out preparation, processing and analysis of tissues or cells. The platform includes a histology space, a cell culture space, a molecular biology space and a small microscopy area.
Equipment
- Neurosurgery equipment in P1 and P2 surgery rooms:
Isoflurane stations, Kopf & RWD Digital Stereotaxic Frames, Leica microscopes - Neurophysiology equipment:
Faraday cage, AD Instruments Power Lab data acquisition system - Histology equipment:
Paraffin embedding stations (Tissue-Tek VIP6, Diapath Canova)
Freezing and sectioning: Excilone Snapfrost, Leica CM 3050S & CM1950 Cryostats, HM 355S Microtome
Staining: Leica Multistainer and coverslipper - Molecular biology equipment:
Automates for DNA or protein analyses and PCR based experiments (Qiagen QIAgility, QIAcube, QIAxcel, QuantStudio 6 Flex) - Cell Culture equipment:
Biological Safety Cabinets, Incubators, Leica DM IL LED microscope
Expertise
- Housing and breeding
- Ethics to combine animal research and ethics compliance to maximize animal welfare
- Genotyping services
- Histology techniques