Over the past weeks and with the threat of emerging variants growing, pressing calls for an open sharing of SARS-CoV-2 sequencing data were issued by the scientific community. Such sharing would allow fast, representative and large-scale research on the virus – but infrastructure and the corresponding investments are often lacking. Echoing these calls, the Swiss Pathogen Surveillance Platform (SPSP) co-led by SIB is now supported by the Swiss Federal authorities to act as the Swiss SARS-CoV-2 Data Hub. Initially developed to track the emergence and spread of any pathogens in Switzerland, SPSP has developed into a user-friendly platform to collect viral genome sequences produced from Swiss samples in the context of the pandemic and submit them notably to the  European Nucleotide Archive (ENA), the reference for open sharing of sequence data.